Drug Standards
Medchemexpress LLC Alverine citrate | 5560-59-8 | MFCD00035086 | 99.5% | 10 G
Alverine citrate is a 5-HT1A receptor antagonist, inhibiting the receptor with an IC50 of 101 nM. It is utilized in the treatment of functional gastrointestinal disorders, acting directly on gut muscles to induce relaxation. In vitro studies demonstrate its high affinity for 5-HT1A receptors and weak affinity for 5-HT3 and 5-HT4 subtypes. This compound is suitable for research applications.
- 5-HT1A receptor antagonist with an IC50 of 101 nM
- Used for functional gastrointestinal disorders
- Acts directly on gut muscle to cause relaxation
- High affinity for 5-HT1A receptors
- Weak affinity for 5-HT3 and 5-HT4 subtypes
- May increase Ca influx and suppress evoked activity
- For research use only
Medchemexpress LLC Fexofenadine | 83799-24-0 | 99.8% | 5 MG
Fexofenadine is an orally active and nonsedative H1 receptor antagonist. It can be used in allergic rhinitis and chronic idiopathic urticarial research.
- Orally active
- Nonsedative H1 receptor antagonist
- Used in allergic rhinitis research
- Used in chronic idiopathic urticarial research
Medchemexpress LLC Porcn-IN-1 | 2036044-77-4 | 99.6% | 410.44 | 50 MG
Porcn-IN-1 is a potent porcupine inhibitor with an IC50 of 0.5±0.2 nM. It potently inhibits the secretion of Wnt3A. Porcupine is an enzyme that catalyzes the addition of palmitoleate to a serine residue in Wnt proteins, a process required for their secretion.
- Potent porcupine inhibitor
- Inhibits secretion of Wnt3A
- Targets Porcupine and is involved in the Stem Cell/Wnt pathway
- As potent as clinical compound LGK974 in cell-based STF reporter gene assay
- Demonstrates moderate clearance in human and rat liver microsomes
- Exhibits high clearance with mouse microsomes
Cayman Chemical MogrosIde V 10mg
A natural cucurbitane glycoside that is used as a low calorie sweetener
Medchemexpress LLC (R)-Ketorolac | 66635-93-6 | 99.65% | 50 MG
(R)-Ketorolac is an orally active inhibitor of Cdc42 and Rac1 GTPases. It has been shown to alter ovarian cancer cell behaviors crucial for invasion and metastasis and can ameliorate cancer-associated cachexia.
- Orally active Cdc42 and Rac1 inhibitor.
- Inhibits GTPase.
- Alters ovarian cancer cell behaviors critical for invasion and metastasis.
- Ameliorates cancer-associated cachexia.
Medchemexpress LLC Ketorolac | 74103-06-3 | 99.9% | 100 MG
Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) that functions as a nonselective COX inhibitor. It is utilized in ophthalmic solutions for various conditions and also serves as a DDX3 inhibitor for cancer research. This product is stable under recommended storage conditions and is intended for laboratory use only.
- Non-steroidal anti-inflammatory drug (NSAID)
- Nonselective COX inhibitor
- Used in ophthalmic solutions
- DDX3 inhibitor for cancer research
- Stable under recommended storage conditions
- For research use only
Medchemexpress LLC Gemcitabine monophosphate | 116371-67-6 | 99.98% | 343.18 | 10 MG
Gemcitabine monophosphate is an active intermediate of Gemcitabine, designed for research use. It exhibits a synergistic anti-cancer effect and can be delivered by formulating it into nanoparticles. It has been shown to induce tumor cell apoptosis and reduce tumor cell proliferation.
- Has a synergistic anti-cancer effect
- Can be delivered by formulating it into nanoparticles
- Induces tumor cell apoptosis (30-40%)
- Reduces tumor cell proliferation (by 8 times)
- Significantly reduces tumor microvessel density (MVD)
- Inhibits tumor mitosis
Medchemexpress LLC Tenofovir exalidex | 911208-73-6 | 99.8% | 569.72 | 100 MG
Tenofovir exalidex (CMX157) is a lipid conjugate of the acyclic nucleotide analog Tenofovir. It is active against both wild-type and antiretroviral drug-resistant HIV strains, including multidrug nucleoside/nucleotide analog-resistant viruses. It is effective against all major subtypes of HIV-1 and HIV-2 in fresh human PBMCs and against all HIV-1 strains evaluated in monocyte-derived macrophages, with EC50s ranging between 0.2 and 7.2 nM. CMX157 is orally available, has no apparent toxicity, and also shows antiviral activity against HBV.
- Consistently >300-fold more active than Tenofovir against multiple viruses
- Effective against MNR mutants unresponsive to currently available NRTIs
- Inhibits HBV polymerase-mediated HBV DNA elongation
Cayman Chemical TemozolomIde AcId 50mg
An active metabolite of temozolomide; cytotoxic to TLX5 murine lymphoma cells; a synthetic intermediate in the synthesis of temozolomide prodrugs with anticancer activity
Sigma Aldrich Fine Chemicals Biosciences Omeprazole Related Compoun50MG
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Sigma Aldrich Fine Chemicals Biosciences Indapamide British Pharmacopoeia (BP) Reference Standard | 26807-65-8 | MFCD00079375 |
Indapamide British Pharmacopoeia (BP) Reference Standard | Mol Wt: 365.83 | 26807-65-8 | MFCD00079375 |